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Fuzzy Interactions Form and Shape the Histone Transport Complex

Protein transport into the nucleus is mediated by transport receptors. Import of highly charged proteins, such as histone H1 and ribosomal proteins, requires a dimer of two transport receptors. In this study, we determined the cryo-EM structure of the Imp7:Impβ:H1.0 complex, showing that the two imp...

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Detalles Bibliográficos
Autores principales: Ivic, Nives, Potocnjak, Mia, Solis-Mezarino, Victor, Herzog, Franz, Bilokapic, Silvija, Halic, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436938/
https://www.ncbi.nlm.nih.gov/pubmed/30824373
http://dx.doi.org/10.1016/j.molcel.2019.01.032