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Selective Disruption of Mitochondrial Thiol Redox State in Cells and In Vivo
Mitochondrial glutathione (GSH) and thioredoxin (Trx) systems function independently of the rest of the cell. While maintenance of mitochondrial thiol redox state is thought vital for cell survival, this was not testable due to the difficulty of manipulating the organelle's thiol systems indepe...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436940/ https://www.ncbi.nlm.nih.gov/pubmed/30713096 http://dx.doi.org/10.1016/j.chembiol.2018.12.002 |