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A Klebsiella pneumoniae Regulatory Mutant Has Reduced Capsule Expression but Retains Hypermucoviscosity

The polysaccharide capsule is an essential virulence factor for Klebsiella pneumoniae in both community-acquired hypervirulent strains as well as health care-associated classical strains that are posing significant challenges due to multidrug resistance. Capsule production is known to be transcripti...

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Detalles Bibliográficos
Autores principales: Walker, Kimberly A., Miner, Taryn A., Palacios, Michelle, Trzilova, Dominika, Frederick, Daniel R., Broberg, Christopher A., Sepúlveda, Victoria E., Quinn, Joshua D., Miller, Virginia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437046/
https://www.ncbi.nlm.nih.gov/pubmed/30914502
http://dx.doi.org/10.1128/mBio.00089-19