Cargando…

A Klebsiella pneumoniae Regulatory Mutant Has Reduced Capsule Expression but Retains Hypermucoviscosity

The polysaccharide capsule is an essential virulence factor for Klebsiella pneumoniae in both community-acquired hypervirulent strains as well as health care-associated classical strains that are posing significant challenges due to multidrug resistance. Capsule production is known to be transcripti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Walker, Kimberly A., Miner, Taryn A., Palacios, Michelle, Trzilova, Dominika, Frederick, Daniel R., Broberg, Christopher A., Sepúlveda, Victoria E., Quinn, Joshua D., Miller, Virginia L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437046/ https://www.ncbi.nlm.nih.gov/pubmed/30914502 http://dx.doi.org/10.1128/mBio.00089-19

Ejemplares similares

The Small Protein RmpD Drives Hypermucoviscosity in Klebsiella pneumoniae
por: Walker, Kimberly A., et al.
Publicado: (2020)

Hypermucoviscosity Regulator RmpD Interacts with Wzc and Controls Capsular Polysaccharide Chain Length
por: Ovchinnikova, Olga G., et al.
Publicado: (2023)

Identification of Two Regulators of Virulence That Are Conserved in Klebsiella pneumoniae Classical and Hypervirulent Strains
por: Palacios, Michelle, et al.
Publicado: (2018)

Enhancement of capsular hypermucoviscosity in Klebsiella pneumoniae by Acanthamoeba
por: Huang, Jian-Ming, et al.
Publicado: (2023)

A systematic analysis of hypermucoviscosity and capsule reveals distinct and overlapping genes that impact Klebsiella pneumoniae fitness
por: Mike, Laura A., et al.
Publicado: (2021)

A Klebsiella variicola Plasmid Confers Hypermucoviscosity-Like Phenotype and Alters Capsule Production and Virulence
por: Rodríguez-Medina, Nadia, et al.
Publicado: (2020)

Assessment of hypermucoviscosity as a virulence factor for experimental Klebsiella pneumoniae infections: comparative virulence analysis with hypermucoviscosity-negative strain
por: Lin, Yi-Chun, et al.
Publicado: (2011)

A Serendipitous Mutation Reveals the Severe Virulence Defect of a Klebsiella pneumoniae fepB Mutant
por: Palacios, Michelle, et al.
Publicado: (2017)

Unusual Hypermucoviscous Clinical Isolate of Klebsiella pneumoniae with No Known Determinants of Hypermucoviscosity
por: Dey, Tamal, et al.
Publicado: (2022)

Klebsiella pneumoniae and the pyogenic liver abscess: implications and association of the presence of rpmA genes and expression of hypermucoviscosity
por: Alcántar-Curiel, María Dolores, et al.
Publicado: (2015)

Change of Hypermucoviscosity in the Development of Tigecycline Resistance in Hypervirulent Klebsiella pneumoniae Sequence Type 23 Strains
por: Park, Suyeon, et al.
Publicado: (2020)

A Case of Hypermucoviscosity Phenotype of Klebsiella pneumoniae Liver Abscess Saved by Damage Control Strategy
por: Sato, Keita, et al.
Publicado: (2022)

Clinical and genomic analysis of hypermucoviscous Klebsiella pneumoniae isolates: Identification of new hypermucoviscosity associated genes
por: Jin, Meiling, et al.
Publicado: (2023)

A Simple Scoring Algorithm That Predicts Abscesses in Adults with Community-Onset Klebsiella pneumoniae Bacteremia: Hypermucoviscosity Matters
por: Hong, Ming-Yuan, et al.
Publicado: (2020)

A case of emphysematous pyelonephritis caused by the hypermucoviscosity phenotype of Klebsiellapneumoniae
por: Kawaguchi, Yoshihiro, et al.
Publicado: (2022)

A Klebsiella pneumoniae ST307 outbreak clone from Germany demonstrates features of extensive drug resistance, hypermucoviscosity, and enhanced iron acquisition
por: Heiden, Stefan E., et al.
Publicado: (2020)

Klebsiella: a long way to go towards understanding this enigmatic jet-setter
por: Broberg, Christopher A., et al.
Publicado: (2014)

The hypermucoviscosity of hypervirulent K. pneumoniae confers the ability to evade neutrophil-mediated phagocytosis
por: Xu, Qi, et al.
Publicado: (2021)

Whole-Genome Draft Sequences of Three Multidrug-Resistant Klebsiella pneumoniae Strains Available from the American Type Culture Collection
por: Broberg, Christopher A., et al.
Publicado: (2013)

Complete Genome Sequence of Klebsiella pneumoniae Strain ATCC 43816 KPPR1, a Rifampin-Resistant Mutant Commonly Used in Animal, Genetic, and Molecular Biology Studies
por: Broberg, Christopher A., et al.
Publicado: (2014)

Retrieval of a retained video capsule endoscope with laparoscopic surgery
por: Jain, Sumita A, et al.
Publicado: (2018)

Laparoscopic Approach for the Retrieval of Retained Video Capsule Endoscopy
por: Dominguez, Edward P., et al.
Publicado: (2006)

Retained anterior capsule: A masquerader of Descemet's membrane detachment
por: Sarkar, Prathama, et al.
Publicado: (2020)

Temperature Control of psaA Expression by PsaE and PsaF in Yersinia pestis
por: Quinn, Joshua D., et al.
Publicado: (2019)

Cell envelope defects of different capsule‐null mutants in K1 hypervirulent Klebsiella pneumoniae can affect bacterial pathogenesis
por: Tan, Yi Han, et al.
Publicado: (2020)

Retained Wireless Capsule Endoscope in a Girl with suspected Crohn’s Disease
por: Herle, Koushik, et al.
Publicado: (2016)

The Capsule Regulatory Network of Klebsiella pneumoniae Defined by density-TraDISort
por: Dorman, Matthew J., et al.
Publicado: (2018)

Intravital Imaging Reveals Divergent Cytokine and Cellular Immune Responses to Candida albicans and Candida parapsilosis
por: Archambault, Linda S., et al.
Publicado: (2019)

Klebsiella pneumoniae capsule polysaccharide as a target for therapeutics and vaccines
por: Opoku-Temeng, Clement, et al.
Publicado: (2019)

Nutrient conditions are primary drivers of bacterial capsule maintenance in Klebsiella
por: Buffet, Amandine, et al.
Publicado: (2021)

Urine-mediated suppression of Klebsiella pneumoniae mucoidy is counteracted by spontaneous Wzc variants altering capsule chain length
por: Khadka, Saroj, et al.
Publicado: (2023)

Defining principles that influence antimicrobial peptide activity against capsulated Klebsiella pneumoniae
por: Fleeman, Renee M., et al.
Publicado: (2020)

Successful Retrieval of a Retained Capsule Endoscope with Single Incision Laparoscopic Surgery
por: Tashiro, Yoshihiko, et al.
Publicado: (2014)

Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage
por: Dunstan, Rhys A., et al.
Publicado: (2021)

Rho factor mediates flagellum and toxin phase variation and impacts virulence in Clostridioides difficile
por: Trzilova, Dominika, et al.
Publicado: (2020)

Flagellum and toxin phase variation impacts intestinal colonization and disease development in a mouse model of Clostridioides difficile infection
por: Trzilova, Dominika, et al.
Publicado: (2022)

Nephromyces Represents a Diverse and Novel Lineage of the Apicomplexa That Has Retained Apicoplasts
por: Muñoz-Gómez, Sergio A, et al.
Publicado: (2019)

Identification of Klebsiella capsule synthesis loci from whole genome data
por: Wyres, Kelly L., et al.
Publicado: (2016)

LPS O Antigen Plays a Key Role in Klebsiella pneumoniae Capsule Retention
por: Singh, Shweta, et al.
Publicado: (2022)

Kaptive Web: User-Friendly Capsule and Lipopolysaccharide Serotype Prediction for Klebsiella Genomes
por: Wick, Ryan R., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_e7sg368gnm43p5k6dhc4g1iisl