Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection

Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in 2012 as a novel etiological agent of severe respiratory disease in humans. As during infection by other viruses, host sensing of viral double-stranded RNA (dsRNA) induces several antiviral pathways. These include interfe...

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Detalles Bibliográficos
Autores principales: Comar, Courtney E., Goldstein, Stephen A., Li, Yize, Yount, Boyd, Baric, Ralph S., Weiss, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437052/
https://www.ncbi.nlm.nih.gov/pubmed/30914508
http://dx.doi.org/10.1128/mBio.00319-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437052/
https://www.ncbi.nlm.nih.gov/pubmed/30914508
http://dx.doi.org/10.1128/mBio.00319-19

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