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Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection
Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in 2012 as a novel etiological agent of severe respiratory disease in humans. As during infection by other viruses, host sensing of viral double-stranded RNA (dsRNA) induces several antiviral pathways. These include interfe...
Autores principales: | Comar, Courtney E., Goldstein, Stephen A., Li, Yize, Yount, Boyd, Baric, Ralph S., Weiss, Susan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437052/ https://www.ncbi.nlm.nih.gov/pubmed/30914508 http://dx.doi.org/10.1128/mBio.00319-19 |
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