Entry of Polarized Effector Cells into Quiescence Forces HIV Latency

The latent HIV reservoir is generated following HIV infection of activated effector CD4 T cells, which then transition to a memory phenotype. Here, we describe an ex vivo method, called QUECEL (quiescent effector cell latency), that mimics this process efficiently and allows production of large numb...

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Detalles Bibliográficos
Autores principales: Dobrowolski, Curtis, Valadkhan, Saba, Graham, Amy C., Shukla, Meenakshi, Ciuffi, Angela, Telenti, Amalio, Karn, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437053/
https://www.ncbi.nlm.nih.gov/pubmed/30914509
http://dx.doi.org/10.1128/mBio.00337-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437053/
https://www.ncbi.nlm.nih.gov/pubmed/30914509
http://dx.doi.org/10.1128/mBio.00337-19

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