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Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction

Exposure to traumatic or infectious insults results in a rapid activation of the complement cascade as major fluid defense system of innate immunity. The complement system acts as a master alarm system during the molecular danger response after trauma and significantly contributes to the clearance o...

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Detalles Bibliográficos
Autores principales: Karasu, Ebru, Nilsson, Bo, Köhl, Jörg, Lambris, John D., Huber-Lang, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437067/
https://www.ncbi.nlm.nih.gov/pubmed/30949180
http://dx.doi.org/10.3389/fimmu.2019.00543