Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease

There is evidence that lower height is associated with a higher risk of coronary artery disease (CAD) and increased risk of type 2 diabetes (T2D). It is not clear though whether these associations are causal, direct or mediated by other factors. Here we show that one standard deviation higher geneti...

Descripción completa

Detalles Bibliográficos
Autores principales: Marouli, Eirini, Del Greco, M. Fabiola, Astley, Christina M., Yang, Jian, Ahmad, Shafqat, Berndt, Sonja I., Caulfield, Mark J., Evangelou, Evangelos, McKnight, Barbara, Medina-Gomez, Carolina, van Vliet-Ostaptchouk, Jana V., Warren, Helen R., Zhu, Zhihong, Hirschhorn, Joel N., Loos, Ruth J. F., Kutalik, Zoltan, Deloukas, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437163/
https://www.ncbi.nlm.nih.gov/pubmed/30937401
http://dx.doi.org/10.1038/s42003-019-0361-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437163/
https://www.ncbi.nlm.nih.gov/pubmed/30937401
http://dx.doi.org/10.1038/s42003-019-0361-2

Ejemplares similares