Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease

There is evidence that lower height is associated with a higher risk of coronary artery disease (CAD) and increased risk of type 2 diabetes (T2D). It is not clear though whether these associations are causal, direct or mediated by other factors. Here we show that one standard deviation higher geneti...

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Detalles Bibliográficos
Autores principales: Marouli, Eirini, Del Greco, M. Fabiola, Astley, Christina M., Yang, Jian, Ahmad, Shafqat, Berndt, Sonja I., Caulfield, Mark J., Evangelou, Evangelos, McKnight, Barbara, Medina-Gomez, Carolina, van Vliet-Ostaptchouk, Jana V., Warren, Helen R., Zhu, Zhihong, Hirschhorn, Joel N., Loos, Ruth J. F., Kutalik, Zoltan, Deloukas, Panos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437163/
https://www.ncbi.nlm.nih.gov/pubmed/30937401
http://dx.doi.org/10.1038/s42003-019-0361-2

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