Sequential conditioning-stimulation reveals distinct gene- and stimulus-specific effects of Type I and II IFN on human macrophage functions

Macrophages orchestrate immune responses by sensing and responding to pathogen-associated molecules. These responses are modulated by prior conditioning with cytokines such as interferons (IFNs). Type I and II IFN have opposing functions in many biological scenarios, yet macrophages directly stimula...

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Detalles Bibliográficos
Autores principales: Cheng, Quen, Behzadi, Faraz, Sen, Supriya, Ohta, Sho, Spreafico, Roberto, Teles, Rosane, Modlin, Robert L., Hoffmann, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437173/
https://www.ncbi.nlm.nih.gov/pubmed/30918279
http://dx.doi.org/10.1038/s41598-019-40503-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437173/
https://www.ncbi.nlm.nih.gov/pubmed/30918279
http://dx.doi.org/10.1038/s41598-019-40503-y

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