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X-ray structures of the high-affinity copper transporter Ctr1

Copper (Cu) is an essential trace element for growth and development and abnormal Cu levels are associated with anemia, metabolic disease and cancer. Evolutionarily conserved from fungi to humans, the high-affinity Cu(+) transporter Ctr1 is crucial for both dietary Cu uptake and peripheral distribut...

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Detalles Bibliográficos
Autores principales: Ren, Feifei, Logeman, Brandon L., Zhang, Xiaohui, Liu, Yongjian, Thiele, Dennis J., Yuan, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437178/
https://www.ncbi.nlm.nih.gov/pubmed/30918258
http://dx.doi.org/10.1038/s41467-019-09376-7