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Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism

Parkinson’s disease (PD) is the second most common neurodegenerative disorder and is characterized by motor deficits such as tremor, rigidity and bradykinesia. These symptoms are directly caused by the loss of dopaminergic neurons. However, a wealth of clinical evidence indicates that the dopaminerg...

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Detalles Bibliográficos
Autores principales: Kreiner, Grzegorz, Rafa-Zabłocka, Katarzyna, Barut, Justyna, Chmielarz, Piotr, Kot, Marta, Bagińska, Monika, Parlato, Rosanna, Daniel, Władysława Anna, Nalepa, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437187/
https://www.ncbi.nlm.nih.gov/pubmed/30918302
http://dx.doi.org/10.1038/s41598-019-41756-3