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Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism
Parkinson’s disease (PD) is the second most common neurodegenerative disorder and is characterized by motor deficits such as tremor, rigidity and bradykinesia. These symptoms are directly caused by the loss of dopaminergic neurons. However, a wealth of clinical evidence indicates that the dopaminerg...
Autores principales: | Kreiner, Grzegorz, Rafa-Zabłocka, Katarzyna, Barut, Justyna, Chmielarz, Piotr, Kot, Marta, Bagińska, Monika, Parlato, Rosanna, Daniel, Władysława Anna, Nalepa, Irena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437187/ https://www.ncbi.nlm.nih.gov/pubmed/30918302 http://dx.doi.org/10.1038/s41598-019-41756-3 |
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