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Directing curli polymerization with DNA origami nucleators

The physiological or pathological formation of fibrils often relies on molecular-scale nucleators that finely control the kinetics and structural features. However, mechanistic understanding of how protein nucleators mediate fibril formation in cells remains elusive. Here, we develop a CsgB-decorate...

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Detalles Bibliográficos
Autores principales: Mao, Xiuhai, Li, Ke, Liu, Mengmeng, Wang, Xinyu, Zhao, Tianxin, An, Bolin, Cui, Mengkui, Li, Yingfeng, Pu, Jiahua, Li, Jiang, Wang, Lihua, Lu, Timothy K., Fan, Chunhai, Zhong, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437208/
https://www.ncbi.nlm.nih.gov/pubmed/30918257
http://dx.doi.org/10.1038/s41467-019-09369-6