Inhibition of USP2 eliminates cancer stem cells and enhances TNBC responsiveness to chemotherapy

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer that harbors enriched cancer stem cell (CSC) populations in tumors. Conventional chemotherapy is a standard treatment for TNBC, but it spares the CSC populations, which cause tumor recurrence and progression. Theref...

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Detalles Bibliográficos
Autores principales: He, Jiabei, Lee, Hong-Jen, Saha, Suchandrima, Ruan, Diane, Guo, Hua, Chan, Chia-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437220/
https://www.ncbi.nlm.nih.gov/pubmed/30918246
http://dx.doi.org/10.1038/s41419-019-1512-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437220/
https://www.ncbi.nlm.nih.gov/pubmed/30918246
http://dx.doi.org/10.1038/s41419-019-1512-6

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