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Determination of a pharmacokinetic model for [(11)C]-acetate in brown adipose tissue

BACKGROUND: [(11)C]-acetate positron emission tomography is used to assess oxidative metabolism in various tissues including the heart, tumor, and brown adipose tissue. For brown adipose tissue, a monoexponential decay model is commonly employed. However, no systematic assessment of kinetic models h...

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Detalles Bibliográficos
Autores principales: Richard, Marie Anne, Blondin, Denis P., Noll, Christophe, Lebel, Réjean, Lepage, Martin, Carpentier, André C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437247/
https://www.ncbi.nlm.nih.gov/pubmed/30919091
http://dx.doi.org/10.1186/s13550-019-0497-6