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Impact of cardiac myosin light chain kinase gene mutation on development of dilated cardiomyopathy

AIMS: Cardiac myosin light chain kinase (cMLCK) phosphorylates ventricular myosin regulatory light chain 2 (MLC2v) and regulates sarcomere and cardiomyocyte organization. However, few data exist regarding the relationship between cMLCK mutations and MLC2v phosphorylation, particularly in terms of de...

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Detalles Bibliográficos
Autores principales: Hodatsu, Akihiko, Fujino, Noboru, Uyama, Yuki, Tsukamoto, Osamu, Imai‐Okazaki, Atsuko, Yamazaki, Satoru, Seguchi, Osamu, Konno, Tetsuo, Hayashi, Kenshi, Kawashiri, Masa‐aki, Asano, Yoshihiro, Kitakaze, Masafumi, Takashima, Seiji, Yamagishi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437445/
https://www.ncbi.nlm.nih.gov/pubmed/30690923
http://dx.doi.org/10.1002/ehf2.12410