Recent progress and challenges in screening and characterization of UGT1A1 inhibitors

Uridine-diphosphate glucuronosyltransferase 1A1 (UGT1A1) is an important conjugative enzyme in mammals that is responsible for the conjugation and detoxification of both endogenous and xenobiotic compounds. Strong inhibition of UGT1A1 may trigger adverse drug/herb–drug interactions, or result in met...

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Detalles Bibliográficos
Autores principales: Lv, Xia, Xia, Yangliu, Finel, Moshe, Wu, Jingjing, Ge, Guangbo, Yang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437557/
https://www.ncbi.nlm.nih.gov/pubmed/30972276
http://dx.doi.org/10.1016/j.apsb.2018.09.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437557/
https://www.ncbi.nlm.nih.gov/pubmed/30972276
http://dx.doi.org/10.1016/j.apsb.2018.09.005

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