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Upregulation of actin cytoskeleton via myocardin leads to increased expression of type 1 collagen
Liver fibrosis is characterized by excessive deposition of extracellular matrix (ECM) in the liver. Although many fibrogenic cell types may express ECM, the hepatic stellate cell (HSC) is currently considered to be the major effector. HSCs transform into myofibroblast-like cells, also known as hepat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437559/ https://www.ncbi.nlm.nih.gov/pubmed/29035375 http://dx.doi.org/10.1038/labinvest.2017.96 |