Repeated cold exposures protect a mouse model of Alzheimer's disease against cold-induced tau phosphorylation

OBJECTIVE: Old age is associated with a rise in the incidence of Alzheimer's disease (AD) but also with thermoregulatory deficits. Indicative of a link between the two, hypothermia induces tau hyperphosphorylation. The 3xTg-AD mouse model not only develops tau and amyloid pathologies in the bra...

Descripción completa

Detalles Bibliográficos
Autores principales: Tournissac, Marine, Bourassa, Philippe, Martinez-Cano, Ruben D., Vu, Tra-My, Hébert, Sébastien S., Planel, Emmanuel, Calon, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437631/
https://www.ncbi.nlm.nih.gov/pubmed/30770297
http://dx.doi.org/10.1016/j.molmet.2019.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437631/
https://www.ncbi.nlm.nih.gov/pubmed/30770297
http://dx.doi.org/10.1016/j.molmet.2019.01.008

Ejemplares similares