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The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice
OBJECTIVE: Administration of glucagon (GCG) or GCG-containing co-agonists reduces body weight and increases energy expenditure. These actions appear to be transduced by multiple direct and indirect GCG receptor (GCGR)-dependent mechanisms. Although the canonical GCGR is expressed in brown adipose ti...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437632/ https://www.ncbi.nlm.nih.gov/pubmed/30772257 http://dx.doi.org/10.1016/j.molmet.2019.01.011 |