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WWOX somatic ablation in skeletal muscles alters glucose metabolism

OBJECTIVE: WWOX, a well-established tumor suppressor, is frequently lost in cancer and plays important roles in DNA damage response and cellular metabolism. METHODS: We re-analyzed several genome-wide association studies (GWAS) using the Type 2 Diabetes Knowledge Portal website to uncover WWOX'...

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Detalles Bibliográficos
Autores principales: Abu-Remaileh, Muhannad, Abu-Remaileh, Monther, Akkawi, Rania, Knani, Ibrahim, Udi, Shiran, Pacold, Micheal E., Tam, Joseph, Aqeilan, Rami I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437662/
https://www.ncbi.nlm.nih.gov/pubmed/30755385
http://dx.doi.org/10.1016/j.molmet.2019.01.010