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In Utero Exposure to Fine Particulate Matter Causes Hypertension Due to Impaired Renal Dopamine D(1) Receptor in Offspring

BACKGROUND/AIMS: Adverse environment in utero can modulate adult phenotypes including blood pressure. Fine particulate matter (PM(2.5)) exposure in utero causes hypertension in the offspring, but the exact mechanisms are not clear. Renal dopamine D(1) receptor (D(1)R), regulated by G protein-coupled...

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Detalles Bibliográficos
Autores principales: Ye, Zhengmeng, Lu, Xi, Deng, Yi, Wang, Xinquan, Zheng, Shuo, Ren, Hongmei, Zhang, Miao, Chen, Tingting, Jose, Pedro A., Yang, Jian, Zeng, Chunyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437669/
https://www.ncbi.nlm.nih.gov/pubmed/29614490
http://dx.doi.org/10.1159/000488418