Efficient bioactive oligonucleotide‐protein conjugation for cell‐targeted cancer therapy

Oligonucleotide‐protein conjugates have important applications in biomedicine. Simple and efficient methods are described for the preparation of these conjugates. Specifically, we describe a new method in which a bifunctional linker is attached to thiol‐oligonucleotide to generate a reactive interme...

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Detalles Bibliográficos
Autores principales: Aviñó, Anna, Unzueta, Ugutz, Virtudes Céspedes, María, Casanova, Isolda, Vázquez, Esther, Villaverde, Antonio, Mangues, Ramon, Eritja, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437810/
https://www.ncbi.nlm.nih.gov/pubmed/30976478
http://dx.doi.org/10.1002/open.201900038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437810/
https://www.ncbi.nlm.nih.gov/pubmed/30976478
http://dx.doi.org/10.1002/open.201900038

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