Dextramabs: A Novel Format of Antibody‐Drug Conjugates Featuring a Multivalent Polysaccharide Scaffold

Antibody‐drug conjugates (ADCs) are multicomponent biomolecules that have emerged as a powerful tool for targeted tumor therapy. Combining specific binding of an immunoglobulin with toxic properties of a payload, they however often suffer from poor hydrophilicity when loaded with a high amount of to...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider, Hendrik, Deweid, Lukas, Pirzer, Thomas, Yanakieva, Desislava, Englert, Simon, Becker, Bastian, Avrutina, Olga, Kolmar, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437811/
https://www.ncbi.nlm.nih.gov/pubmed/30976476
http://dx.doi.org/10.1002/open.201900066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437811/
https://www.ncbi.nlm.nih.gov/pubmed/30976476
http://dx.doi.org/10.1002/open.201900066

Ejemplares similares