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Predicting enhancers in mammalian genomes using supervised hidden Markov models

BACKGROUND: Eukaryotic gene regulation is a complex process comprising the dynamic interaction of enhancers and promoters in order to activate gene expression. In recent years, research in regulatory genomics has contributed to a better understanding of the characteristics of promoter elements and f...

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Detalles Bibliográficos
Autores principales: Zehnder, Tobias, Benner, Philipp, Vingron, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437899/
https://www.ncbi.nlm.nih.gov/pubmed/30917778
http://dx.doi.org/10.1186/s12859-019-2708-6