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Predicting enhancers in mammalian genomes using supervised hidden Markov models
BACKGROUND: Eukaryotic gene regulation is a complex process comprising the dynamic interaction of enhancers and promoters in order to activate gene expression. In recent years, research in regulatory genomics has contributed to a better understanding of the characteristics of promoter elements and f...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437899/ https://www.ncbi.nlm.nih.gov/pubmed/30917778 http://dx.doi.org/10.1186/s12859-019-2708-6 |