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Topconfects: a package for confident effect sizes in differential expression analysis provides a more biologically useful ranked gene list
Differential gene expression analysis may discover a set of genes too large to easily investigate, so a means of ranking genes by biological interest level is desired. p values are frequently abused for this purpose. As an alternative, we propose a method of ranking by confidence bounds on the log f...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437914/ https://www.ncbi.nlm.nih.gov/pubmed/30922379 http://dx.doi.org/10.1186/s13059-019-1674-7 |