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RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3

BACKGROUND: N6-methyladenosine (m6A) modification is the most pervasive modification in mRNA, and has been considered as a new layer of epigenetic regulation on mRNA processing, stability and translation. Despite its functional significance in various physiological processes, the role of the m6A mod...

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Detalles Bibliográficos
Autores principales: Niu, Yi, Lin, Ziyou, Wan, Arabella, Chen, Honglei, Liang, Heng, Sun, Lei, Wang, Yuan, Li, Xi, Xiong, Xiao-feng, Wei, Bo, Wu, Xiaobin, Wan, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437932/
https://www.ncbi.nlm.nih.gov/pubmed/30922314
http://dx.doi.org/10.1186/s12943-019-1004-4