Effect of low complexity regions within the PvMSP3α block II on the tertiary structure of the protein and implications to immune escape mechanisms

BACKGROUND: Plasmodium vivax merozoite surface protein 3α (PvMSP3α) is a promising vaccine candidate which has shown strong association with immunogenicity and protectiveness. Its use is however complicated by evolutionary plasticity features which enhance immune evasion. Low complexity regions (LCR...

Descripción completa

Detalles Bibliográficos
Autores principales: Kebede, Alebachew Messele, Tadesse, Fitsum Girma, Feleke, Adey Desta, Golassa, Lemu, Gadisa, Endalamaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437935/
https://www.ncbi.nlm.nih.gov/pubmed/30917807
http://dx.doi.org/10.1186/s12900-019-0104-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437935/
https://www.ncbi.nlm.nih.gov/pubmed/30917807
http://dx.doi.org/10.1186/s12900-019-0104-0

Ejemplares similares