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Effect of low complexity regions within the PvMSP3α block II on the tertiary structure of the protein and implications to immune escape mechanisms

BACKGROUND: Plasmodium vivax merozoite surface protein 3α (PvMSP3α) is a promising vaccine candidate which has shown strong association with immunogenicity and protectiveness. Its use is however complicated by evolutionary plasticity features which enhance immune evasion. Low complexity regions (LCR...

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Detalles Bibliográficos
Autores principales:	Kebede, Alebachew Messele, Tadesse, Fitsum Girma, Feleke, Adey Desta, Golassa, Lemu, Gadisa, Endalamaw
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437935/ https://www.ncbi.nlm.nih.gov/pubmed/30917807 http://dx.doi.org/10.1186/s12900-019-0104-0

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