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Algorithm-supported, mass and sequence diversity-oriented random peptide library design

Random peptide libraries that cover large search spaces are often used for the discovery of new binders, even when the target is unknown. To ensure an accurate population representation, there is a tendency to use large libraries. However, parameters such as the synthesis scale, the number of librar...

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Detalles Bibliográficos
Autores principales: Kalafatovic, Daniela, Mauša, Goran, Todorovski, Toni, Giralt, Ernest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437963/
https://www.ncbi.nlm.nih.gov/pubmed/30923940
http://dx.doi.org/10.1186/s13321-019-0347-6