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Algorithm-supported, mass and sequence diversity-oriented random peptide library design
Random peptide libraries that cover large search spaces are often used for the discovery of new binders, even when the target is unknown. To ensure an accurate population representation, there is a tendency to use large libraries. However, parameters such as the synthesis scale, the number of librar...
Autores principales: | Kalafatovic, Daniela, Mauša, Goran, Todorovski, Toni, Giralt, Ernest |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437963/ https://www.ncbi.nlm.nih.gov/pubmed/30923940 http://dx.doi.org/10.1186/s13321-019-0347-6 |
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