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Genetic polymorphisms of histone methyltransferase SETD2 predicts prognosis and chemotherapy response in Chinese acute myeloid leukemia patients

BACKGROUND: SETD2, the single mediator of trimethylation of histone 3 at position lysine 36, has been reported associated with initiation progression and chemotherapy resistance in acute myeloid leukemia (AML). Whether polymorphisms of SETD2 affect prognosis and chemotherapy response of AML remains...

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Detalles Bibliográficos
Autores principales: Wang, Suwei, Yuan, Xiaoqing, Liu, Yazhen, Zhu, Kewei, Chen, Peng, Yan, Han, Zhang, Daoyu, Li, Xi, Zeng, Hui, Zhao, Xielan, Chen, Xiaoping, Zhou, Gan, Cao, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437967/
https://www.ncbi.nlm.nih.gov/pubmed/30922329
http://dx.doi.org/10.1186/s12967-019-1848-9