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Development of novel and safer anti-breast cancer agents, SS1020 and SS5020, based on a fundamental carcinogenic research
Tamoxifen (TAM) has been prescribed worldwide to patients with and women at high-risk of breast cancer. However, long-term use of TAM increases the incidence of endometrial cancer. The carcinogenic mechanisms of TAM have been extensively investigated. TAM is hydroxylated and sulfonated at α-carbon t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437986/ https://www.ncbi.nlm.nih.gov/pubmed/30976361 http://dx.doi.org/10.1186/s41021-019-0124-9 |