Alevin efficiently estimates accurate gene abundances from dscRNA-seq data

We introduce alevin, a fast end-to-end pipeline to process droplet-based single-cell RNA sequencing data, performing cell barcode detection, read mapping, unique molecular identifier (UMI) deduplication, gene count estimation, and cell barcode whitelisting. Alevin’s approach to UMI deduplication con...

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Detalles Bibliográficos
Autores principales: Srivastava, Avi, Malik, Laraib, Smith, Tom, Sudbery, Ian, Patro, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437997/
https://www.ncbi.nlm.nih.gov/pubmed/30917859
http://dx.doi.org/10.1186/s13059-019-1670-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437997/
https://www.ncbi.nlm.nih.gov/pubmed/30917859
http://dx.doi.org/10.1186/s13059-019-1670-y

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