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Alevin efficiently estimates accurate gene abundances from dscRNA-seq data

We introduce alevin, a fast end-to-end pipeline to process droplet-based single-cell RNA sequencing data, performing cell barcode detection, read mapping, unique molecular identifier (UMI) deduplication, gene count estimation, and cell barcode whitelisting. Alevin’s approach to UMI deduplication con...

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Detalles Bibliográficos
Autores principales:	Srivastava, Avi, Malik, Laraib, Smith, Tom, Sudbery, Ian, Patro, Rob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437997/ https://www.ncbi.nlm.nih.gov/pubmed/30917859 http://dx.doi.org/10.1186/s13059-019-1670-y

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