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Plasma protein adsorption on Fe(3)O(4)-PEG nanoparticles activates the complement system and induces an inflammatory response

BACKGROUND: Understanding of iron oxide nanoparticles (IONP) interaction with the body milieu is crucial to guarantee their efficiency and biocompatibility in nanomedicine. Polymer coating to IONP, with polyethyleneglycol (PEG) and polyvinylpyrrolidone (PVP), is an accepted strategy to prevent toxic...

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Detalles Bibliográficos
Autores principales: Escamilla-Rivera, V, Solorio-Rodríguez, A, Uribe-Ramírez, M, Lozano, O, Lucas, S, Chagolla-López, A, Winkler, R, De Vizcaya-Ruiz, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438142/
https://www.ncbi.nlm.nih.gov/pubmed/30988608
http://dx.doi.org/10.2147/IJN.S192214