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Transient Expression of GATA3 in Hematopoietic Stem Cells Facilitates Helper Innate Lymphoid Cell Differentiation

Helper Innate lymphoid cells (ILCs) are tissue resident lymphocytes that play a critical role in a number of biological processes. Several transcription factors are required for the differentiation of hematopoietic stem cells (HSCs) into ILCs. Recent studies demonstrate GATA3 as a transcriptional re...

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Detalles Bibliográficos
Autores principales: Tufa, Dejene M., Yingst, Ashley M., Shank, Tyler, Shim, Seonhui, Trahan, George Devon, Lake, Jessica, Woods, Renee, Jones, Kenneth L., Verneris, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438154/
https://www.ncbi.nlm.nih.gov/pubmed/30949172
http://dx.doi.org/10.3389/fimmu.2019.00510