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Cancer cachexia impairs neural respiratory drive in hypoxia but not hypercapnia

BACKGROUND: Cancer cachexia is an insidious process characterized by muscle atrophy with associated motor deficits, including diaphragm weakness and respiratory insufficiency. Although neuropathology contributes to muscle wasting and motor deficits in many clinical disorders, neural involvement in c...

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Detalles Bibliográficos
Autores principales: Fields, Daryl P., Roberts, Brandon M., Simon, Alec K., Judge, Andrew R., Fuller, David D., Mitchell, Gordon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438337/
https://www.ncbi.nlm.nih.gov/pubmed/30362273
http://dx.doi.org/10.1002/jcsm.12348