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A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis

Chronic hepatitis B is one of the world’s unconquered diseases with more than 240 million infected subjects at risk of developing liver disease and hepatocellular carcinoma. Hepatitis B virus reverse transcribes pre-genomic RNA to relaxed circular DNA (rcDNA) that comprises the infectious particle....

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Detalles Bibliográficos
Autores principales: Wing, Peter AC, Davenne, Tamara, Wettengel, Jochen, Lai, Alvina G, Zhuang, Xiaodong, Chakraborty, Anindita, D’Arienzo, Valentina, Kramer, Catharina, Ko, Chunkyu, Harris, James M, Schreiner, Sabrina, Higgs, Martin, Roessler, Stephanie, Parish, Joanna L, Protzer, Ulrike, Balfe, Peter, Rehwinkel, Jan, McKeating, Jane A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438393/
https://www.ncbi.nlm.nih.gov/pubmed/30918010
http://dx.doi.org/10.26508/lsa.201900355