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Sodium-coupled monocarboxylate transporter is a target of epigenetic repression in cervical cancer

The SLC5A8 gene encodes Na monocarboxylate transporter 1, which is epigenetically inactivated in various tumour types. This has been attributed to the fact that it prevents the entry of histone deacetylase (HDAC) inhibitors and favours the metabolic reprogramming of neoplastic cells. Nevertheless, i...

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Detalles Bibliográficos
Autores principales: Hernández-Juárez, Jennifer, Vargas-Sierra, Orlando, Herrera, Luis A., De León, David Cantú, Fernández-Retana, Jorge, Pérez-Plasencia, Carlos, López-Camarillo, César, Gariglio, Patricio, Díaz-Chávez, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438420/
https://www.ncbi.nlm.nih.gov/pubmed/30896789
http://dx.doi.org/10.3892/ijo.2019.4749