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Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers
At the root of the so-called precision medicine or precision oncology, which is our focus here, is the hypothesis that cancer treatment would be considerably better if therapies were guided by a tumor’s genomic alterations. This hypothesis has sparked major initiatives focusing on whole-genome and/o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438456/ https://www.ncbi.nlm.nih.gov/pubmed/30921324 http://dx.doi.org/10.1371/journal.pcbi.1006658 |