A systems pharmacology workflow with experimental validation to assess the potential of anakinra for treatment of focal and segmental glomerulosclerosis

Focal and Segmental Glomerulosclerosis (FSGS) is a severe glomerulopathy that frequently leads to end stage renal disease. Only a subset of patients responds to current therapies, making it important to identify alternative therapeutic options. The interleukin (IL)-1 receptor antagonist anakinra is...

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Detalles Bibliográficos
Autores principales: Boehm, Michael, Bukosza, Eva Nora, Huttary, Nicole, Herzog, Rebecca, Aufricht, Christoph, Kratochwill, Klaus, Gebeshuber, Christoph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438574/
https://www.ncbi.nlm.nih.gov/pubmed/30921378
http://dx.doi.org/10.1371/journal.pone.0214332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438574/
https://www.ncbi.nlm.nih.gov/pubmed/30921378
http://dx.doi.org/10.1371/journal.pone.0214332

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