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Evidence that alternative transcriptional initiation is largely nonadaptive

Alternative transcriptional initiation (ATI) refers to the frequent observation that one gene has multiple transcription start sites (TSSs). Although this phenomenon is thought to be adaptive, the specific advantage is rarely known. Here, we propose that each gene has one optimal TSS and that ATI ar...

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Detalles Bibliográficos
Autores principales: Xu, Chuan, Park, Joong-Ki, Zhang, Jianzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438578/
https://www.ncbi.nlm.nih.gov/pubmed/30883542
http://dx.doi.org/10.1371/journal.pbio.3000197