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Evidence that alternative transcriptional initiation is largely nonadaptive
Alternative transcriptional initiation (ATI) refers to the frequent observation that one gene has multiple transcription start sites (TSSs). Although this phenomenon is thought to be adaptive, the specific advantage is rarely known. Here, we propose that each gene has one optimal TSS and that ATI ar...
Autores principales: | Xu, Chuan, Park, Joong-Ki, Zhang, Jianzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438578/ https://www.ncbi.nlm.nih.gov/pubmed/30883542 http://dx.doi.org/10.1371/journal.pbio.3000197 |
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