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Cytoskeletal alteration modulates cancer cell invasion through RhoA-YAP signaling in stromal fibroblasts

Cancer-associated fibroblasts(CAFs) participate in carcinogenesis through interaction with cancer cells. This study aimed to investigate the mechanism of cytoskeletal alteration of CAFs and its role in invasion of oral squamous cell carcinoma(OSCC).Immortalized normal fibroblasts(hTERT-hNOFs) co-cul...

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Detalles Bibliográficos
Autores principales: Kim, Do Kyeong, Kim, Eun Kyoung, Jung, Da-Woon, Kim, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438594/
https://www.ncbi.nlm.nih.gov/pubmed/30921404
http://dx.doi.org/10.1371/journal.pone.0214553