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Intramolecular domain dynamics regulate synaptic MAGUK protein interactions

PSD-95 MAGUK family scaffold proteins are multi-domain organisers of synaptic transmission that contain three PDZ domains followed by an SH3-GK domain tandem. This domain architecture allows coordinated assembly of protein complexes composed of neurotransmitter receptors, synaptic adhesion molecules...

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Detalles Bibliográficos
Autores principales: Rademacher, Nils, Kuropka, Benno, Kunde, Stella-Amrei, Wahl, Markus C, Freund, Christian, Shoichet, Sarah A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438691/
https://www.ncbi.nlm.nih.gov/pubmed/30864948
http://dx.doi.org/10.7554/eLife.41299