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Intramolecular domain dynamics regulate synaptic MAGUK protein interactions
PSD-95 MAGUK family scaffold proteins are multi-domain organisers of synaptic transmission that contain three PDZ domains followed by an SH3-GK domain tandem. This domain architecture allows coordinated assembly of protein complexes composed of neurotransmitter receptors, synaptic adhesion molecules...
Autores principales: | Rademacher, Nils, Kuropka, Benno, Kunde, Stella-Amrei, Wahl, Markus C, Freund, Christian, Shoichet, Sarah A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438691/ https://www.ncbi.nlm.nih.gov/pubmed/30864948 http://dx.doi.org/10.7554/eLife.41299 |
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